PROTAC SMARCA2 degrader-24
PROTAC SMARCA2 degrader-24 (Compound 34) is a potent, selective degrader of the SMARCA2 bromodomain protein, demonstrating a DC50 100-fold selectivity over SMARCA4. This tool compound is used in vitro to probe SWI/SNF chromatin remodeling complex biology and for targeted protein degradation research.
Product Specifications
CAS Number
2755761-70-5
Field of Research
Epigenetics & Chromatin, Neuroscience, Pharmacology & Drug Discovery
Smiles
C (CN (CCC=1C=C (C (C (=O) N2[C@H] (C (N[C@@H] (C) C3=CC=C (C=C3) C=4SC=NC4C) =O) C[C@@H] (O) C2) C (C) C) ON1) C) N5C[C@]6 (N (C=7C (NC6) =NN=C (C7) C8=C (O) C=CC=C8) CC5) [H]
Molecular Formula
C45H56N10O5S
Molecular Weight
849.06
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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