SJ46421
SJ46421 is a potent PROTAC derived from (+) -JQ-1 that selectively recruits the E3 ligase KLHDC2 to degrade BRD2/3/4 BD2 domains. It demonstrates high ternary complex stability with an IC50 of 7.8 nM, making it a valuable chemical probe for BET protein function studies in cancer and epigenetic research, applicable in both cellular and biochemical assays.
Product Specifications
Field of Research
Epigenetics & Chromatin, Pharmacology & Drug Discovery
Molecular Formula
C42H41ClN8O5S2
Molecular Weight
837.41
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
ARP48274_P050 100 µL
ALDOC antibody - C-terminal region (ARP48274_P050)
Sign In for Pricing
View Details 
GTR15103140 1 Vial
Lentiviral human MDH2 shRNA (UAS) - Lentiviral human MDH2 shRNA (UAS, RFP) (100)
Sign In for Pricing
View Details K4579503 1.0 µg DNA
Dus4l sgRNA CRISPR Lentivector (Mouse) (Target 2)
Sign In for Pricing
View Details MBS2508600-01 24 Tests (Limit 1)
Rat MBP (Myelin Basic Protein) ELISA Kit
Sign In for Pricing
View Details