PS-166276
PS-166276 is a highly potent and selective p38 MAPK inhibitor, demonstrating an IC50 of 28 nM against the kinase and 170 nM in a cellular THP-1 TNFα assay. This compound is a valuable research tool for investigating p38-mediated pathways in inflammation, oncology, and cellular stress responses in both in vitro and in vivo models.
Product Specifications
CAS Number
348089-57-6
Field of Research
Signal Transduction
Smiles
N (C=1N=C (N[C@@H]2CCNC2) N=C (N (CC (C) C) C) N1) C3=CC (C (N) =O) =CC=C3C
Molecular Formula
C20H30N8O
Molecular Weight
398.51
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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