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PROTAC SMARCA2 degrader-25

PROTAC SMARCA2 degrader-25 (example 86) potently induces targeted protein degradation with a DC50 below 10 nM. This tool compound is valuable for probing SMARCA2 biology in cancer research and has demonstrated utility in both cellular and in vivo preclinical studies.

Product Specifications

CAS Number

2770571-17-8

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Smiles

C (=O) (N1C[C@]2 (N (C=3C (=NN=C (C3) C4=C (O) C=CC=C4) NC2) CC1) [H]) C5CCN (CC6CN (C6) C=7C=C8C (=CC7) C (=O) N (C8=O) C9C (=O) NC (=O) CC9) CC5

Molecular Formula

C38H41N9O6

Molecular Weight

719.79

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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