RET-IN-27
RET-IN-27 (compound 20p) is a highly potent RET inhibitor with single-digit nanomolar IC50 values against wild-type and multiple oncogenic mutants (RETV804L, RETV804M, RETM918T) . This small molecule is a valuable chemical tool for investigating RET-driven oncogenesis in both cellular and animal models of cancers such as medullary thyroid carcinoma.
Product Specifications
Field of Research
Cell Biology, Signal Transduction
Molecular Formula
C31H28N8O
Molecular Weight
528.61
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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