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RET-IN-27

RET-IN-27 (compound 20p) is a highly potent RET inhibitor with single-digit nanomolar IC50 values against wild-type and multiple oncogenic mutants (RETV804L, RETV804M, RETM918T) . This small molecule is a valuable chemical tool for investigating RET-driven oncogenesis in both cellular and animal models of cancers such as medullary thyroid carcinoma.

Product Specifications

Field of Research

Cell Biology, Signal Transduction

Molecular Formula

C31H28N8O

Molecular Weight

528.61

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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