Keap1-Nrf2-IN-23
Keap1-Nrf2-IN-23 (compound 56) is a potent, orally active small molecule inhibitor of the Keap1-Nrf2 protein-protein interaction, with an IC50 of 16.0 nM and a Kd of 3.07 nM for Keap1. It is a valuable research tool for investigating the Nrf2 pathway in oxidative stress and inflammation models, both in vitro and in vivo.
Product Specifications
CAS Number
2771115-65-0
Field of Research
Cancer Biology, Immunology & Inflammation
Smiles
O=C (O) CC (C1=CC=2N=NN (C2C (OC) =C1) C) C=3C=CC=C4C3CCN (C (=O) C5=CC=C (OC (C) C) C=C5Cl) C4
Molecular Formula
C30H31ClN4O5
Molecular Weight
563.04
Storage Conditions
-20°C
Notes
For research use only.
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