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WK692

Compound WK692 is a potent and selective BCL6 inhibitor for research use. It demonstrates synergistic activity with EZH2 and PRMT5 inhibitors in suppressing diffuse large B-cell lymphoma (DLBCL) cell proliferation in vitro, showing efficacy without significant toxicity in preclinical models.

Product Specifications

CAS Number

2694055-38-2

Field of Research

Immunology & Inflammation

Smiles

N (C=1N2C (N=C (C1) N3[C@@H] (COC (CBr) =O) CCC3) =NC=N2) C=4C=C5C (=CC4) N (C) C (=O) C (OCCNC (CBr) =O) =C5

Molecular Formula

C26H28Br2N8O5

Molecular Weight

692.36

Storage Conditions

-20°C

Notes

For research use only.

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NFKB1 (KBF1, NF-kappaB, NFkappaB, NF-kB1, NFKB-p50, EBP-1, p50, p105, TRANSCRIPTION FACTOR NFKB1, DNA-binding factor KBF1, NFKB p50, INCLUDED, NFKB p105, INCLUDED, Nuclear factor of kappa light polypeptide gene enhancer in B Cells 1) (MaxLight 550)
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