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ZLC491

ZLC491 is an orally bioavailable PROTAC molecule designed to degrade CDK12 and CDK13. It is used in cancer research to study transcription-dependent cancers and has demonstrated degradation activity in both cellular and animal models.

Product Specifications

CAS Number

3053716-46-1

Field of Research

Cell Biology, Pharmacology & Drug Discovery

Smiles

O=C1C=2C (C (=O) N1C3C (=O) NC (=O) CC3) =CC (F) =C (C2) N4CCC (CC4) N5CCN (CC5) C6=CC=C (N (C (NCC7=CC=CC=C7) =O) [C@@H]8CC[C@@H] (NC9=CC=C (C#N) C=N9) CC8) C=C6

Molecular Formula

C48H51FN10O5

Molecular Weight

866.98

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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