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PROTAC HDAC8 Degrader-2

PROTAC HDAC8 Degrader-2 (compound 32a) is a heterobifunctional degrader that recruits the CRBN E3 ligase to degrade HDAC8 (DC50 = 8.9 nM) and HDAC6 (DC50 = 14.3 nM) . It is a valuable chemical tool for probing HDAC isoform functions in cancer and neurobiology research, both in vitro and in vivo.

Product Specifications

Field of Research

Epigenetics & Chromatin, Pharmacology & Drug Discovery

Molecular Formula

C39H44N10O8

Molecular Weight

780.83

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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