Dyrk1A-IN-11
Dyrk1A-IN-11 (compound 166) is a potent small molecule inhibitor of DYRK1A (EC50 = 0.0021 μM) and also suppresses Tau phosphorylation at Thr212 (EC50 = 0.0361 μM) . This compound is a valuable research tool for investigating DYRK1A and tau-related mechanisms in neurodegenerative disease models, both in vitro and in vivo.
Product Specifications
CAS Number
3058626-26-6
Field of Research
Cell Biology, Signal Transduction
Smiles
FC=1C (=C2N (C1) N=C (N[C@H]3C (F) (F) CN (CC3) C4COC4) N=C2) C=5N=C6C (=CC5) N=C (C) N6CC (F) F
Molecular Formula
C23H23F5N8O
Molecular Weight
522.47
Storage Conditions
-20°C
Notes
For research use only.
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