EGFR-IN-131
EGFR-IN-131 (3a) is a brain-penetrant EGFR inhibitor (IC50 = 272.9 nM) that suppresses cancer cell proliferation by downregulating p-EGFR, inducing apoptosis, and arresting the cell cycle at G0/G1 phase. It is a valuable tool for in vitro and in vivo studies of EGFR-driven cancers, including those with CNS involvement.
Product Specifications
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Molecular Formula
C26H23FN4O2S
Molecular Weight
474.55
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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