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EGFR-IN-131

EGFR-IN-131 (3a) is a brain-penetrant EGFR inhibitor (IC50 = 272.9 nM) that suppresses cancer cell proliferation by downregulating p-EGFR, inducing apoptosis, and arresting the cell cycle at G0/G1 phase. It is a valuable tool for in vitro and in vivo studies of EGFR-driven cancers, including those with CNS involvement.

Product Specifications

Field of Research

Cardiovascular Research, Cell Biology, Signal Transduction

Molecular Formula

C26H23FN4O2S

Molecular Weight

474.55

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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