GA 0113
GA 0113 is a potent and orally bioavailable angiotensin II AT1 receptor antagonist. It effectively blocks Ang II-induced hypertension with an ID50 of 0.032 mg/kg and induces a sustained, dose-dependent increase in plasma renin activity. This compound is a valuable research tool for investigating the renin-angiotensin system in cardiovascular and renal disease models.
Product Specifications
CAS Number
200639-61-8
Field of Research
Metabolism Research
Smiles
O=S (=O) (NC=1C=CC=CC1C2=NC=3C=CC (=CC3C=C2) CN4C5=NC (=CC (=C5N=C4CC) C) C) C (F) (F) F
Molecular Formula
C27H24F3N5O2S
Molecular Weight
539.57
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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