KRAS inhibitor-37
KRAS inhibitor-37 is a potent small molecule with sub-nanomolar affinity for multiple KRAS mutants, including G12D, G12C, and G12V. It demonstrates strong anti-proliferative activity in various cancer cell lines (IC50 <2-14 nM), making it a valuable tool for in vitro and in vivo oncology research targeting RAS-driven cancers.
Product Specifications
CAS Number
3058573-95-5
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
FC=1C=2C3=C (N4[C@] (COC3=NC1C=5C (=C (Cl) C=C6C5C=NN6) C7CC7) (COCCC4) [H]) N=C (OC[C@@]89N (CC (=C) C8) CCC9) N2
Molecular Formula
C32H33ClFN7O3
Molecular Weight
618.10
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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