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YJ9069

YJ9069 is a potent and selective CDK12/CDK13 PROTAC degrader (IC50 = 22.22 nM in VCaP cells) . It induces transcription-dependent DNA damage and cell cycle arrest, effectively inhibiting prostate cancer cell proliferation in vitro and suppressing tumor growth in vivo, making it a valuable tool for oncology and targeted protein degradation research.

Product Specifications

Field of Research

Cell Biology, Molecular Biology, Pharmacology & Drug Discovery

Molecular Formula

C46H46N10O7

Molecular Weight

850.92

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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