YJ9069
YJ9069 is a potent and selective CDK12/CDK13 PROTAC degrader (IC50 = 22.22 nM in VCaP cells) . It induces transcription-dependent DNA damage and cell cycle arrest, effectively inhibiting prostate cancer cell proliferation in vitro and suppressing tumor growth in vivo, making it a valuable tool for oncology and targeted protein degradation research.
Product Specifications
Field of Research
Cell Biology, Molecular Biology, Pharmacology & Drug Discovery
Molecular Formula
C46H46N10O7
Molecular Weight
850.92
Storage Conditions
-20°C
Notes
For research use only.
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