3-Azaspiro[5.5]undecane (hydrochloride)

3-Azaspiro[5.5]undecane (4,4-Pentamethylenepiperidine) hydrochloride is an inhibitor targeting the WT influenza A virus M2 (A/M2), with an IC50 of 1 μM[1].

Product Specifications

CAS Number

[1125-01-5]

Product Name Alternative

4,4-Pentamethylenepiperidine (hydrochloride)

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H332, H335

Target

Influenza Virus

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/3-azaspiro-5-5-undecane-hydrochloride.html

Purity

97.0

Solubility

H2O : 100 mg/mL (ultrasonic)

Smiles

[H]Cl.C12(CCNCC2)CCCCC1

Molecular Formula

C10H20ClN

Molecular Weight

189.73

Precautions

H302, H315, H319, H332, H335

References & Citations

[1]Wang J, et al. Exploring the Requirements for the Hydrophobic Scaffold and Polar Amine in inhibitors of M2 from Influenza A Virus. ACS Med Chem Lett. 2011 Apr 14;2 (4) :307-312.