ATG7-IN-1

ATG7-IN-1 (Compound 37) is a potent and selective inhibitor of ATG7 (IC50 = 62 nM) .

Product Specifications

CAS Number

[2226229-87-2]

UNSPSC

12352005

Target

Atg7; Autophagy

Type

Reference compound

Related Pathways

Autophagy

Applications

COVID-19-immunoregulation

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/atg7-in-1.html

Purity

99.91

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

NS(OC[C@@H]([C@H](C1)O)O[C@@]1([H])N2C3=NC=NC(N)=C3C(SC4=C(C=C(C=C4)C)F)=N2)(=O)=O

Molecular Formula

C17H19FN6O5S2

Molecular Weight

470.50

References & Citations

[1]Huang SC, et al. Discovery and optimization of pyrazolopyrimidine sulfamates as ATG7 inhibitors. Bioorg Med Chem. 2020 Oct 1;28 (19) :115681.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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