ATG7-IN-1
Product Specifications
UNSPSC Description
ATG7-IN-1 is a potent and selective inhibitor of ATG7 (IC50 = 62 nM).
Target Antigen
Atg7; Autophagy
Type
Reference compound
Related Pathways
Autophagy
Applications
COVID-19-immunoregulation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/atg7-in-1.html
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
NS(OC[C@@H]([C@H](C1)O)O[C@@]1([H])N2C3=NC=NC(N)=C3C(SC4=C(C=C(C=C4)C)F)=N2)(=O)=O
Molecular Weight
470.50
References & Citations
[1]Huang SC, et al. Discovery and optimization of pyrazolopyrimidine sulfamates as ATG7 inhibitors. Bioorg Med Chem. 2020 Oct 1;28(19):115681.
Shipping Conditions
Blue Ice
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-145371/ATG7-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-145371/ATG7-IN-1-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2226229-87-2
Available Sizes
Curated Selection
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