Antibacterial agent 247

Antibacterialagent 247 (compound 30b) is a small molecule antagonist that potently inhibits Pseudomonas aeruginosa biofilm formation (IC50=5.8 μM) and virulence. It demonstrates synergistic effects with tobramycin and polymyxin B, making it a valuable tool for researching anti-virulence strategies and combination therapies against resistant infections in vitro.