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WRN inhibitor 12

WRN inhibitor 12 (compound 5) is a small molecule that selectively targets and inhibits the Werner syndrome ATP-dependent helicase (WRN) . This tool compound is used in vitro to study DNA repair mechanisms and synthetic lethality in microsatellite unstable (MSI) cancer models.

Product Specifications

CAS Number

3044040-29-8

Field of Research

Cell Biology, Epigenetics & Chromatin; Pharmacology & Drug Discovery, Molecular Biology

Smiles

O=C (C1=NC=NC (=C1O) C) N2CC3N (C=4C (=O) N5N=C (N=C5N (C4CC) CC (=O) NC6=CC=C (C=C6Cl) C (F) (F) F) C7=CCOCC7) C (C2) CC3

Molecular Formula

C33H33ClF3N9O5

Molecular Weight

728.12

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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