SIAIS562055
SIAIS562055 is a cereblon-based SOS1 PROTAC degrader with a Kd of 95.9 nM. It disrupts KRASG12C/SOS1 and KRASG12D/SOS1 interactions and inhibits the ERK pathway, demonstrating potent anticancer activity in cellular studies. This molecule is a valuable research tool for investigating RAS-driven cancers in vitro.
Product Specifications
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Molecular Formula
C49H62F3N7O5S
Molecular Weight
918.12
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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