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SIAIS562055

SIAIS562055 is a cereblon-based SOS1 PROTAC degrader with a Kd of 95.9 nM. It disrupts KRASG12C/SOS1 and KRASG12D/SOS1 interactions and inhibits the ERK pathway, demonstrating potent anticancer activity in cellular studies. This molecule is a valuable research tool for investigating RAS-driven cancers in vitro.

Product Specifications

Field of Research

Pharmacology & Drug Discovery, Signal Transduction

Molecular Formula

C49H62F3N7O5S

Molecular Weight

918.12

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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