What is the catalog number for ZX703?

The catalog number for ZX703 is orb2695184.

What sizes are available for ZX703?

ZX703 is available in the following size(s): 1 mg, 5 mg, 10 mg, 25 mg, 50 mg.

How many pack sizes does ZX703 come in?

ZX703 is available in 5 different pack sizes.

ZX703 is currently made to order / not held in immediate stock. Contact us for lead time.

ZX703

ZX703 is a PROTAC molecule that induces GPX4 degradation via dual ubiquitin-proteasome and autophagy-lysosome pathways (DC50 = 0.315 μM) . This degradation triggers lipid ROS accumulation and ferroptosis, providing a research tool for studying this cell death mechanism in cancer models both in vitro and in vivo.

Product Specifications

Field of Research

Metabolism Research, Pharmacology & Drug Discovery

Purity

99.72% (May vary between batches)

Smiles

CC1=C (SC=N1) C2=CC=C (C=C2) CNC (=O) [C@@H]3C[C@H] (CN3C (=O) [C@H] (C (C) (C) C) NC (=O) CCCCCCCCCOC4=CC=C (C=C4) C (C5=CC=C (C=C5) Cl) N6CCN (CC6) C (=O) C7=NOC (=C7[N+] (=O) [O-]) C) O