D34-919
D34-919 is a small molecule that potently disrupts the ALDH1A3-PKM2 interaction, blocking PKM2 tetramerization. This action restores apoptosis and enhances radiochemotherapy sensitivity in glioblastoma models, as demonstrated in both in vitro and in vivo studies.
Product Specifications
CAS Number
1011641-78-3
Field of Research
Metabolism Research
Smiles
N#CC=1C (=NC (=NC1N2CCC (C (=O) N) CC2) SC) C=3C=CC (=CC3) C (C) (C) C
Molecular Formula
C22H27N5OS
Molecular Weight
409.55
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS9017494 Inquire
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) GT11 Polyclonal Antibody
Sign In for Pricing
View Details 
K1518004 1.0 µg DNA
OR5BA1P sgRNA CRISPR Lentivector (Human) (Target 3)
Sign In for Pricing
View Details orb782821-01 48 Tests
Cattle Pregnancy Associated glycoprotein 1 (PAG1) ELISA Kit
Sign In for Pricing
View Details orb782821-02 96 Tests
Cattle Pregnancy Associated glycoprotein 1 (PAG1) ELISA Kit
Sign In for Pricing
View Details MBS6295459-01 0.2 mL
EMID2, ID (EMID2, COL26A1, EMU2, Collagen alpha-1(XXVI) chain, EMI domain-containing protein 2, Emilin and multimerin domain-containing protein 2) (Biotin)
Sign In for Pricing
View Details