D34-919
D34-919 is a small molecule that potently disrupts the ALDH1A3-PKM2 interaction, blocking PKM2 tetramerization. This action restores apoptosis and enhances radiochemotherapy sensitivity in glioblastoma models, as demonstrated in both in vitro and in vivo studies.
Product Specifications
CAS Number
1011641-78-3
Field of Research
Metabolism Research
Smiles
N#CC=1C (=NC (=NC1N2CCC (C (=O) N) CC2) SC) C=3C=CC (=CC3) C (C) (C) C
Molecular Formula
C22H27N5OS
Molecular Weight
409.55
Storage Conditions
-20°C
Notes
For research use only.
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