AZ 14145845
AZ 14145845 is a potent, orally bioavailable dual Mer/Axl kinase inhibitor. It demonstrates dose-dependent antitumor efficacy in Ba/F3 xenograft models and enhances survival in MC38 tumor models when combined with anti-PD1 therapy and radiation. This compound is a valuable research tool for investigating TAM kinase signaling in immuno-oncology and combination therapies.
Product Specifications
CAS Number
2830555-70-7
Smiles
N=1N=C (OC1C=2N=CC (=CC2C) C=3C (=NN (C3C) C) C) N (C) CC=4C=CC5=NC=C (C=6C=CC (=CC6) CN (C) C) N5C4
Molecular Formula
C32H35N9O
Molecular Weight
561.68
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
K4992205 3x 1.0 µg
Gtf2h1 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)
Sign In for Pricing
View Details Pdgfra-99M 50 µg
Recombinant Mouse Pdgfra Protein, His (Fc)-Avi-tagged
Sign In for Pricing
View Details 16203064 1.0 µg DNA
CISD3 Lentiviral Vector (Mouse) (CMV) (pLenti-GIII-CMV)
Sign In for Pricing
View Details