PB2
PB2 is a tris (2-carboxyethyl) phosphine (TCEP) analogue increasing retinal ganglion (RGCs) cells survival after axotomy in vitro at nanomolar and picomolar concentrations. PB2 is substantially more permeable than TCEP. PB2, as a reducing agent, is highly neuroprotective for RGCs[1].
Product Specifications
CAS Number
914940-24-2
UNSPSC
12352005
Target
Influenza Virus
Type
Reference compound
Related Pathways
Anti-infection
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pb2.html
Purity
99.84
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
[H-][B+3]([P](CCC(OC)=O)(C1=CC=CC=C1)C2=CC=CC=C2)([H-])[H-]
Molecular Formula
C16H20BO2P
Molecular Weight
286.11
References & Citations
[1]Schlieve CR, et al. Synthesis and characterization of a novel class of reducing agents that are highly neuroprotective for retinal ganglion cells. Exp Eye Res. 2006;83 (5) :1252-1259.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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