SHP389
SHP389 is a potent and selective allosteric SHP2 inhibitor, effectively suppressing SHP2 activity and downstream p-ERK signaling. It is a valuable research tool for investigating oncogenic pathways in cancers driven by RTK/RAS signaling, with utility in both cellular and animal model studies.
Product Specifications
CAS Number
2235394-90-6
Product Name Alternative
SHP389, SHP-389, SHP 389
Field of Research
Cell Biology, Metabolism Research, Signal Transduction
Purity
98.24% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (10.31 mM) ; DMSO:80 mg/mL (164.96 mM)
Smiles
N[C@H]1C2 (CCN (CC2) C3=NC=4C (C (=O) N3C) =C (NN4) C=5C (Cl) =C (NC6CC6) N=CC5) CO[C@H]1C
Molecular Formula
C23H29ClN8O2
Molecular Weight
484.98
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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