Tomatidine
Tomatidine acts as an anti-inflammatory agent by blocking NF-κB and JNK signaling[1]. Tomatidine activates autophagy either in mammal cells or C elegans[2].
Product Specifications
CAS Number
77-59-8
UNSPSC
12352005
Hazard Statement
H302
Target
Autophagy; Endogenous Metabolite; JNK; NF-κB
Type
Natural Products
Related Pathways
Autophagy; MAPK/ERK Pathway; Metabolic Enzyme/Protease; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/Tomatidine.html
Purity
98.0
Solubility
0.1 M HCl : < 1 mg/mL|DMSO : 2 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
[H][C@]1(O[C@]2(NC[C@@H](C)CC2)[C@H]3C)C[C@@]4([H])[C@]5([H])CC[C@@]6([H])C[C@@H](O)CC[C@]6(C)[C@@]5([H])CC[C@]4(C)[C@]13[H]
Molecular Formula
C27H45NO2
Molecular Weight
415.65
Precautions
H302
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
JNK; RelA/p65
Available Sizes
Frequently Asked Questions
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