PROTAC PIN1 degrader-1
PROTAC PIN1 degrader-1 is a potent and selective degrader of the PIN1 protein, demonstrating a DC50 of 18 nM in MDA-MB-468 triple-negative breast cancer cells. This research compound is a valuable chemical tool for studying PIN1's role in oncology, supporting both in vitro and in vivo cancer research applications.
Product Specifications
CAS Number
3038591-59-9
Field of Research
Pharmacology & Drug Discovery
Smiles
N#CC=1C=CC (=CC1) C2=CC=C (C=C2) N3N=NC (=C3) CC (NC (=O) C4 (C5=NC=CC=C5C) CC4) C (=O) NC6CCN (CCCCCOC7=CC=CC=8C (=O) N (C (=O) C78) C9C (=O) NC (=O) CC9) CC6
Molecular Formula
C51H52N10O7
Molecular Weight
917.02
Storage Conditions
-20°C
Notes
For research use only.
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