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PROTAC PIN1 degrader-1

PROTAC PIN1 degrader-1 is a potent and selective degrader of the PIN1 protein, demonstrating a DC50 of 18 nM in MDA-MB-468 triple-negative breast cancer cells. This research compound is a valuable chemical tool for studying PIN1's role in oncology, supporting both in vitro and in vivo cancer research applications.

Product Specifications

CAS Number

3038591-59-9

Field of Research

Pharmacology & Drug Discovery

Smiles

N#CC=1C=CC (=CC1) C2=CC=C (C=C2) N3N=NC (=C3) CC (NC (=O) C4 (C5=NC=CC=C5C) CC4) C (=O) NC6CCN (CCCCCOC7=CC=CC=8C (=O) N (C (=O) C78) C9C (=O) NC (=O) CC9) CC6

Molecular Formula

C51H52N10O7

Molecular Weight

917.02

Storage Conditions

-20°C

Notes

For research use only.

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