ER-076349
ER-076349, a Halichondrin B analog, is a microtubule polymerization inhibitor that induces G2/M arrest and disrupts mitotic spindles. It demonstrates potent anti-proliferative activity in cancer cell lines in vitro and suppresses tumor growth in human xenograft mouse models in vivo.
Product Specifications
CAS Number
253128-15-3
Field of Research
Signal Transduction
Smiles
C=C1C[C@@]2 (CC[C@@]34O[C@@]5 ([C@]6 ([C@] ([C@@] (O3) ([C@@] (C4) (O6) [H]) [H]) (O[C@@]7 ([C@@]5 (O[C@] (CC7) (CC (=O) C[C@]8 ([C@@] (O[C@H] (C[C@@H] (CO) O) [C@@H]8OC) (C[C@]9 (O[C@@] (CC[C@@]1 (O2) [H]) (C[C@@H] (C) C9=C) [H]) [H]) [H]) [H]) [H]) [H]) [H]) [H]) [H]) [H]) [H]
Molecular Formula
C40H58O12
Molecular Weight
730.88
Storage Conditions
-20°C
Notes
For research use only.
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