(S, R, S) -AHPC-O-CF3
(S, R, S) -AHPC-O-CF3 is a ligand for the VHL E3 ubiquitin ligase, commonly employed in PROTAC design. It serves as a key component in bifunctional degraders like PROTAC SMARCA2/4-degrader-20, used in vitro to target bromodomain proteins for cancer research.
Product Specifications
CAS Number
2641373-92-2
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery
Smiles
C ([C@H] (C (C) (C) C) N) (=O) N1[C@H] (C (NCC2=C (OC (F) (F) F) C=C (C=C2) C3=C (C) N=CS3) =O) C[C@@H] (O) C1
Molecular Formula
C23H29F3N4O4S
Molecular Weight
514.56
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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