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(S, R, S) -AHPC-O-CF3

(S, R, S) -AHPC-O-CF3 is a ligand for the VHL E3 ubiquitin ligase, commonly employed in PROTAC design. It serves as a key component in bifunctional degraders like PROTAC SMARCA2/4-degrader-20, used in vitro to target bromodomain proteins for cancer research.

Product Specifications

CAS Number

2641373-92-2

Field of Research

Immunology & Inflammation, Pharmacology & Drug Discovery

Smiles

C ([C@H] (C (C) (C) C) N) (=O) N1[C@H] (C (NCC2=C (OC (F) (F) F) C=C (C=C2) C3=C (C) N=CS3) =O) C[C@@H] (O) C1

Molecular Formula

C23H29F3N4O4S

Molecular Weight

514.56

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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