HRX-0233
HRX-0233 is a MAP2K4 inhibitor that effectively shrinks H358 KRASG12C NSCLC tumors in vivo with minimal toxicity. It enhances KRAS inhibitor therapy by blocking RTK feedback, sustaining MAPK pathway suppression, and shows research potential in prostate, lung, and colon cancer models.
Product Specifications
CAS Number
2409140-12-9
Field of Research
Epigenetics & Chromatin, Signal Transduction
Purity
99.59% (May vary between batches)
Smiles
O=C (C1=CC=C (F) C (NS (=O) (=O) CCC) =C1F) C2=CNC3=NC=C (C=C32) C=4C=NC (=NC4) C5CC5
Molecular Formula
C24H21F2N5O3S
Molecular Weight
497.52
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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