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KRAS inhibitor-31

KRAS inhibitor-31 (compound 33) is a highly potent small molecule binder of KRAS G12D, G12C, and G12V mutants, with SPR-measured K D values of 0.019 nM, 0.019 nM, and 0.096 nM, respectively. This tool compound is suitable for in vitro biochemical and cellular studies of oncogenic KRAS signaling and inhibition.

Product Specifications

CAS Number

2920695-77-6

Field of Research

Pharmacology & Drug Discovery, Signal Transduction

Smiles

FC=1C=2C3=C (N4[C@] (COC3=NC1C=5C6=C (C=C (O) C5) C=CC (F) =C6C#C) (COCCC4) [H]) N=C (OC[C@@]78N (C[C@H] (F) C7) CCC8) N2

Molecular Formula

C33H30F3N5O4

Molecular Weight

617.62

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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