KRAS inhibitor-31
KRAS inhibitor-31 (compound 33) is a highly potent small molecule binder of KRAS G12D, G12C, and G12V mutants, with SPR-measured K D values of 0.019 nM, 0.019 nM, and 0.096 nM, respectively. This tool compound is suitable for in vitro biochemical and cellular studies of oncogenic KRAS signaling and inhibition.
Product Specifications
CAS Number
2920695-77-6
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
FC=1C=2C3=C (N4[C@] (COC3=NC1C=5C6=C (C=C (O) C5) C=CC (F) =C6C#C) (COCCC4) [H]) N=C (OC[C@@]78N (C[C@H] (F) C7) CCC8) N2
Molecular Formula
C33H30F3N5O4
Molecular Weight
617.62
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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