Ch282-5
Ch282-5 is an orally bioavailable Bcl-2 inhibitor that induces mitochondria-dependent apoptosis in colorectal cancer cells by disrupting mitophagy and mTOR signaling, showing efficacy in both in vitro and in vivo models. It also enhances Oxaliplatin-induced autophagy and can mitigate thrombocytopenia, supporting its investigation in combination therapies.
Product Specifications
CAS Number
65891-87-4
Field of Research
Cell Biology
Smiles
O=C1C2=C (C (C (C) =C1C (C (C3=C4C (C (C) C) =C (O) C (O) =C3C=NCCS (=O) ([O-]) =O) =O) =C (C) C4=O) =O) C (C (C) C) =C (O) C (O) =C2C=NCCS (=O) ([O-]) =O.[Na+].[Na+]
Molecular Formula
C34H34N2Na2O14S2
Molecular Weight
804.75
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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