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Ch282-5

Ch282-5 is an orally bioavailable Bcl-2 inhibitor that induces mitochondria-dependent apoptosis in colorectal cancer cells by disrupting mitophagy and mTOR signaling, showing efficacy in both in vitro and in vivo models. It also enhances Oxaliplatin-induced autophagy and can mitigate thrombocytopenia, supporting its investigation in combination therapies.

Product Specifications

CAS Number

65891-87-4

Field of Research

Cell Biology

Smiles

O=C1C2=C (C (C (C) =C1C (C (C3=C4C (C (C) C) =C (O) C (O) =C3C=NCCS (=O) ([O-]) =O) =O) =C (C) C4=O) =O) C (C (C) C) =C (O) C (O) =C2C=NCCS (=O) ([O-]) =O.[Na+].[Na+]

Molecular Formula

C34H34N2Na2O14S2

Molecular Weight

804.75

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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