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G-631

G-631 is a potent and selective tankyrase inhibitor with an IC50 of 7 nM against auto-PARsylation, leading to suppression of the Wnt/β-catenin pathway. It is a valuable chemical probe for studying Wnt-driven cancers and stem cell biology in both cellular and mouse models, supported by its favorable in vivo pharmacokinetics.

Product Specifications

CAS Number

1507370-78-6

Field of Research

Epigenetics & Chromatin, Molecular Biology

Smiles

O=C1N=C (NC2=C1C=NN2C) N3CCN (C4=C (F) C=C (OCCOC) C=C4F) CC3

Molecular Formula

C19H22F2N6O3

Molecular Weight

420.41

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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