5-Hydroxyindole-3-acetic acid-d6
5-Hydroxyindole-3-acetic acid-d6 is the deuterium labeled 5-Hydroxyindole-3-acetic acid. 5-Hydroxyindole-3-acetic acid is the main metabolite of serotonin or metanephrines, which can be used as a biomarker of neuroendocrine tumors.
Product Specifications
CAS Number
2748469-82-9
UNSPSC
12352005
Target
Endogenous Metabolite; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Cancer; Neurological Disease
Purity
99.0
Solubility
10 mM in DMSO|Ethanol : 50mg/mL (ultrasonic)
Smiles
OC1=C([2H])C(C(C([2H])([2H])C(O)=O)=C([2H])N2)=C2C([2H])=C1[2H]
Molecular Formula
C10H3D6NO3
Molecular Weight
197.22
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Corcuff JB, et al. Urinary sampling for 5HIAA and metanephrines determination: revisiting the recommendations. Endocr Connect. 2017 Aug;6 (6) :R87-R98.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
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