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PROTAC YAP degrader-1

PROTAC YAP degrader-1 is a bifunctional chimera that induces YAP degradation and blocks its nuclear translocation. It is composed of a Demethyl-NSC682769-based YAP ligand linked to an (R, S, R) -AHPC E3 ligase recruiter via an Acid-PEG2-C2-Boc spacer. This tool compound enables the study of Hippo pathway signaling in cancer research through targeted protein degradation in cellular models.

Product Specifications

Field of Research

Cancer Biology, Pharmacology & Drug Discovery, Stem Cell & Developmental Biology

Molecular Formula

C56H62N6O9S

Molecular Weight

995.19

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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