PROTAC YAP degrader-1
PROTAC YAP degrader-1 is a bifunctional chimera that induces YAP degradation and blocks its nuclear translocation. It is composed of a Demethyl-NSC682769-based YAP ligand linked to an (R, S, R) -AHPC E3 ligase recruiter via an Acid-PEG2-C2-Boc spacer. This tool compound enables the study of Hippo pathway signaling in cancer research through targeted protein degradation in cellular models.
Product Specifications
Field of Research
Cancer Biology, Pharmacology & Drug Discovery, Stem Cell & Developmental Biology
Molecular Formula
C56H62N6O9S
Molecular Weight
995.19
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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