SIJ1777
SIJ1777, a GNF-7 derivative, is a potent small molecule inhibitor for research on BRAF-mutant melanoma. It suppresses oncogenic signaling by inhibiting MEK/ERK and AKT activation, leading to apoptosis and the inhibition of cell migration, invasion, and colony growth in vitro.
Product Specifications
CAS Number
839707-55-0
Field of Research
Cell Biology, Signal Transduction
Purity
99.96% (May vary between batches)
Smiles
O=C (NC1=CC=C (C (=C1) N2C (=O) N (C3=NC (=NC=C3C2) NC4=NN (C=C4) C) C) C) C5=CC=CC (=C5) C (F) (F) F
Molecular Formula
C26H23F3N8O2
Molecular Weight
536.51
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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