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SIJ1777

SIJ1777, a GNF-7 derivative, is a potent small molecule inhibitor for research on BRAF-mutant melanoma. It suppresses oncogenic signaling by inhibiting MEK/ERK and AKT activation, leading to apoptosis and the inhibition of cell migration, invasion, and colony growth in vitro.

Product Specifications

CAS Number

839707-55-0

Field of Research

Cell Biology, Signal Transduction

Purity

99.96% (May vary between batches)

Smiles

O=C (NC1=CC=C (C (=C1) N2C (=O) N (C3=NC (=NC=C3C2) NC4=NN (C=C4) C) C) C) C5=CC=CC (=C5) C (F) (F) F

Molecular Formula

C26H23F3N8O2

Molecular Weight

536.51

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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