17-Demethoxy-reblastatin
17-Demethoxy-reblastatin (17-DR) is an Hsp90 inhibitor that demonstrates anti-cancer activity in vitro by inhibiting proliferation and colony formation in HepG2 and SMMC7721 cells. It induces apoptosis through a mitochondrial and caspase-dependent pathway, making it a useful tool for oncology and molecular chaperone research.
Product Specifications
CAS Number
299173-64-1
Field of Research
Cell Biology, Metabolism Research, Signal Transduction
Smiles
CO[C@H]1CC\C=C (C) /C (=O) NC2=CC (C[C@@H] (C) C[C@H] (OC) [C@H] (O) [C@@H] (C) \C=C (C) \[C@H]1OC (N) =O) =CC (O) =C2
Molecular Formula
C28H42N2O7
Molecular Weight
518.64
Storage Conditions
-20°C
Notes
For research use only.
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