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HURAT1 inhibitor 1

Compound 27b (hURAT1 inhibitor 1) is an orally active, isomarine-derived dual inhibitor of hURAT1 and GLUT9, demonstrating potent anti-hyperuricemic activity in a mouse model at 10 mg/kg. It shows favorable pharmacokinetics and no significant cytotoxicity or hepatotoxicity, making it a valuable research tool for studying urate transporter biology and hyperuricemia therapeutics.

Product Specifications

Field of Research

Metabolism Research, Pharmacology & Drug Discovery

Molecular Formula

C24H19BrO4

Molecular Weight

451.31

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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