HURAT1 inhibitor 1
Compound 27b (hURAT1 inhibitor 1) is an orally active, isomarine-derived dual inhibitor of hURAT1 and GLUT9, demonstrating potent anti-hyperuricemic activity in a mouse model at 10 mg/kg. It shows favorable pharmacokinetics and no significant cytotoxicity or hepatotoxicity, making it a valuable research tool for studying urate transporter biology and hyperuricemia therapeutics.
Product Specifications
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Molecular Formula
C24H19BrO4
Molecular Weight
451.31
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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