Tubulin polymerization-IN-68
Tubulin polymerization-IN-68 is a potent small molecule tubulin polymerization inhibitor that induces apoptosis via PARP-1 and caspase-3 upregulation. It demonstrates potent in vitro anticancer activity against HepG2 cells (IC50 = 93 nM) and has shown significant oral efficacy in reducing HepG2 xenograft tumor growth in nude mouse models.
Product Specifications
CAS Number
2924156-96-5
Field of Research
Cell Biology, Epigenetics & Chromatin, Molecular Biology, Protein Biochemistry, Signal Transduction
Smiles
O=C1NC (NC=2C=CC=CC12) C=3C=CC=4NC=CC4C3
Molecular Formula
C16H13N3O
Molecular Weight
263.29
Storage Conditions
-20°C
Notes
For research use only.
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