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(R) -SCH 546738

(R) -SCH 546738 is a potent and selective non-competitive antagonist of the human CXCR3 receptor (K_i = 0.4 nM) . This orally bioavailable small molecule is a valuable research tool for investigating the role of CXCR3 in autoimmune diseases, transplant rejection, and cancer in both in vitro and in vivo models.

Product Specifications

CAS Number

2181148-54-7

Field of Research

Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery, Signal Transduction

Smiles

ClC=1C (N2C[C@@H] (CC) N (CC2) C3CCN (CC4=CC=C (Cl) C=C4) CC3) =NC (N) =C (C (N) =O) N1

Molecular Formula

C23H31Cl2N7O

Molecular Weight

492.45

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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